Breast Surgery · Implant-Free Autoaugmentation
The Three-Flap Technique: A Modification of Autoaugmentation Mastopexy in a Single-Surgeon Case Series
This retrospective single-surgeon series describes an implant-free mastopexy using three caudally based parenchymal flaps in selected patients with mild-to-moderate ptosis. Among 284 patients assessed at 3 months, contour instability was reported in 3.1% and delayed T-junction healing in 10.6%; the authors call for comparative studies.
Hand Reconstruction · Local Adipofascial Flap
Dorsal Turnover Adipo-Fascial Homo-Digital Flap, a Versatile Coverage Solution for Exposed Finger's Dorsum
This clinical series presents a local dorsal turnover adipofascial flap for coverage of exposed structures on the dorsal finger. The authors report satisfactory soft-tissue coverage and aesthetic results, positioning the method as a technically straightforward local option.
Elbow Reconstruction · Thinned ALT Flap
Single-stage elbow reconstruction using thinned anterolateral thigh flaps: technical insights from perforator anatomy
The technical report details perforator-aware thinning of anterolateral thigh flaps for single-stage elbow reconstruction. It distinguishes primary thinning for single-perforator flaps from more extensive microdissection when multiple perforators provide a vascular safety margin.
Breast-Conserving Surgery · Perforator Flaps
The Role of Intercostal Artery Perforator (ICAP) Flaps in the Transition From Cosmetic to Effective Modern Breast Surgery
This review describes how lateral, anterior, and medial intercostal artery perforator flaps can replace volume after breast-conserving surgery while preserving underlying muscle. It outlines defect-specific flap selection and discusses intraoperative perfusion assessment for buried flaps.
Diabetic Foot Ulcers · Matrix Adjunct · Randomized Trial
A Composite Ovine Forestomach Matrix and Hyaluronic Acid CAMP for the Treatment of Full Thickness Wounds of the Foot in People With Diabetes: A Randomized Controlled Trial
In a multicenter randomized trial of 143 participants with eligible chronic full-thickness diabetic foot wounds, ovine forestomach matrix combined with hyaluronic acid and standard care increased 12-week closure compared with standard care alone. The result applies to the trial’s selected population and specified care regimen.
Hard-to-Heal Ulcers · Regenerative Matrix Adjunct
A Prospective Cohort Study of Hard-to-Heal Chronic Foot and Leg Wounds Followed for up to 20 Weeks After Initiation of ReGenerating Tissue Agents (RGTA) Technology as an Add-on to Optimal Local Care
In this open-label cohort, 173 patients with difficult-to-heal ulcers received a heparan-sulfate-mimetic regenerative agent alongside optimal local care. Closure by 20 weeks was 28.9% in the intention-to-treat group and 40.4% per protocol, with substantial differences by ulcer type and meaningful loss to follow-up; controlled trials are needed.
Diabetic Wounds · Copper Dressing vs NPWT · RCT
Noninferiority of Copper Dressings Than Negative Pressure Wound Therapy in Healing Diabetic Wounds: A Randomized Clinical Trial
In a randomized trial of 46 patients with noninfected diabetic wounds, copper oxide-impregnated dressings were noninferior to negative-pressure therapy for wound-size reduction. Closure proportions were 47.8% versus 34.8%, while application time and estimated treatment cost favored the copper dressings; the small sample limits precision.
Chronic Lower-Limb Ulcers · Vacuum Compression · RCT
Effects of Vacuum Compression Therapy on Healing of Chronic Lower Limb Ulcers: A Randomised Controlled Study
Fifty patients with chronic lower-limb ulcers were randomized to vacuum compression plus standard care or standard care alone. This exploratory study found greater reductions in wound dimensions and improved quality of life with the adjunct, but complete closure during the four-week treatment period was uncommon.
Breast Reconstruction · ADM Timing
Timing of Acellular Dermal Matrix Placement in 2-Stage Breast Reconstruction: Effects on Contracture and Complications
In prepectoral two-stage implant reconstruction, placing ADM at implant exchange was associated with fewer Baker grade III/IV contractures than placing it at the first stage (4.4% vs 25.0%). Delayed placement was also associated with more seroma among patients receiving radiotherapy or axillary dissection, supporting individualized timing and mitigation.
Neonatal Abdominal Wall · Human ADM and NPWT
Application of Acellular Human Dermal Matrix in Neonatal Abdominal Wall Reconstruction with Inadequate Skin Coverage: A Case Report
A human acellular dermal matrix covered a large abdominal-wall defect in a medically fragile neonate when primary closure and skin coverage were not feasible, with negative-pressure therapy over the exposed matrix. Revascularization and epithelialization developed over nine months, and no additional reconstruction was needed during four years of follow-up; this is a single case.
Extracellular Vesicles · Engineered Cell Sources
Synergistic Wound Healing Enhancement by Extracellular Vesicles From Engineered Macrophages and Fibroblasts
The investigators engineered macrophages and fibroblasts to increase extracellular-vesicle yield and tested the combined vesicles in cell and murine full-thickness wound models. The combination enhanced pro-angiogenic and anti-inflammatory signaling and accelerated re-epithelialization, but remains preclinical.
Infected Wounds · Exosome-Mimetic Microneedle Patch
Exosome-mimetic vesicle-encapsulated multi-responsive antibacterial hydrogel core-shell microneedle patch promotes scarless healing of infected wounds
A responsive core-shell microneedle patch couples antibacterial copper oxide with fibroblast-derived exosome-mimetic vesicles carrying a scar-modulating agent. Rat infected-wound and rabbit scar models showed faster healing and scarless regeneration, an early-stage result that still requires clinical translation.
Skin Rejuvenation · Stem Cells and Exosomes
Stem Cell-Based Therapies for Skin Rejuvenation: A Systematic Review
This review synthesizes clinical evidence on stem-cell and exosome approaches for skin rejuvenation. Four human exosome studies involving 148 participants reported wrinkle reductions of 16.8% to 25.4%, but the overall evidence was low to moderate certainty and long-term signals need confirmation.
Facial Rejuvenation · Dual-Wavelength Picosecond Laser
Facial Lifting and Skin Rejuvenation Using a Dual-Wavelength Picosecond Nd:YAG Laser
In a prospective single-arm pilot involving 20 adults, three sessions of sequential 1064- and 532-nm picosecond Nd:YAG treatment were followed by improvements in skin elasticity, tone, pores, wrinkles, and pigmentation. The short follow-up and lack of a control group mean efficacy and durability remain uncertain.
Nonablative Laser · Human Histology
Temporal Histological Tissue Responses Following Fractional Nonablative 1470 nm Laser Exposure: A Pilot In Vivo Human Study
Skin biopsies from 18 healthy adults showed localized micro-injury after fractional 1470-nm laser exposure, followed by re-epithelialization by day 3 and restored epidermal continuity by day 10. This small mechanistic study informs short-term tissue response, not clinical effectiveness or long-term safety.
Photodamage · Multimodal Light and Laser Pilot
A Pilot Study Combining Intense Pulsed Light, Hybrid Fractional 1470/2940-nm Laser, and Fractionated 1927-nm Laser for Diffuse Pigmentation and Actinic Changes
In a prospective study of 15 adults, a combined IPL and fractional-laser protocol improved several pigmentation and texture measures, with greater reductions in UV-spot contrast after two sessions. Reported symptoms were mild and transient, but the small nonrandomized cohort cannot establish comparative efficacy.
Laser & Light-Based Devices · Clinical Evidence Review
Aesthetic Applications of Laser and Light-Based Energy Devices
This review surveys laser and light-based technologies for resurfacing, vascular and pigment lesions, scars, and photoaging. It describes the trade-offs among ablative, nonablative, fractional, picosecond, and combination approaches, emphasizing patient selection and phototype-specific settings to reduce complications.
Fat Graft Survival · Enhancement Strategies
Optimizing Autologous Fat Grafting: A Systematic Review of Enhancement Strategies and Graft Survival
This systematic review compares strategies intended to improve fat-graft survival, including stromal vascular fraction, adipose-derived stem-cell enrichment, and platelet-rich plasma. Enrichment appears promising, but heterogeneity in methods and outcome measurement limits confident selection of a single best approach.
Breast Reconstruction · Latissimus Dorsi Flap and Lipofilling
Comparative Study of Myocutaneous Latissimus Dorsi Flap Breast Reconstruction With Implant Versus Lipofilling: Complication Rates and Risk Factors
A two-center retrospective cohort of 116 patients compared implant-augmented latissimus dorsi flaps with lipofilling for volume restoration. The lipofilling group had fewer early infections and no late reconstruction losses from implant-related problems in this cohort, while overall major-complication differences were not statistically significant.
Burn Reconstruction · Machine-Learning Risk Estimator
Development and Validation of the Skin Graft Loss Risk Estimator: An Interpretable Machine Learning-Driven Tool for Individualized Assessment in Burn Patients
Using 24,046 patients who underwent autologous skin grafting in a large burn registry, investigators developed and tested an interpretable random-forest model for graft-loss risk. Test-set AUC-ROC was 0.794, and the model was translated into a web-based estimator; external prospective validation is still important before clinical reliance.
Reconstructive Surgery · 3D Bioprinting
Three-Dimensional Bioprinting in Reconstructive Plastic Surgery: A Comprehensive Review
This review surveys 3D bioprinting applications relevant to reconstructive plastic surgery, including the potential to create patient-specific tissue constructs and reduce dependence on donor tissue. Clinical translation remains limited by challenges in vascularization, construct function, reproducibility, and regulatory readiness.
Auricular Reconstruction · 3D Printing and Tissue Engineering
Three-Dimensional Printing and Tissue Engineering in Auricular Reconstruction: Global Trends, Research Frontiers, and a Translational Evidence Map
This evidence map combines bibliometric analysis with a translational review of 169 publications on 3D printing and tissue engineering for ear reconstruction. Most evidence remained in vitro or small-animal, with few comparative clinical studies, emphasizing the need to evaluate vascularization, mechanics, shape retention, and safety rather than publication volume alone.
Plastic Surgery · AI Tools and Workflow
AI Tools in Plastic Surgery: A Scoping Review
This scoping review organizes plastic-surgery AI tools across clinical efficiency, imaging and documentation, communication, workflow, and research. It highlights applications in 2D/3D planning, postoperative communication, literature work, and free-flap monitoring, while noting that clinical utility and validation vary across tools.