Breast Reconstruction · Salvage Flap Strategy
Use of the Same Donor Site After Prior Muscle-Sparing Latissimus Dorsi Flap for Salvaging Implant-Based Reconstructive Failures
This report describes seven patients who returned for salvage reconstruction using residual back soft tissue after an earlier muscle-sparing latissimus dorsi flap. The authors suggest that preserving skin and muscle at the first operation may leave a future “lifeboat” option for selected patients at high risk of implant reconstruction failure.
Ear Reconstruction · Surgical Craft & Digital Planning
Evolution of Craft Skills in Ear Reconstruction: A Narrative Review From the Perspectives of an Anaplastologist and a Plastic Surgeon
This narrative review traces auricular reconstruction from early skin-flap methods to refined autologous rib frameworks, alloplastic implants, and contemporary digital and tissue-engineering approaches. CAD-CAM and 3D printing can reduce selected manual steps, but the review emphasizes that technical judgment and aesthetic craft remain central to individualized prosthetic or surgical planning.
Diabetic Burns · Sprayable Hydrogel
Targeting SIRT3 Dysfunction With a Sprayable Honokiol Hydrogel for Diabetic Burn Wound Repair
In diabetic burn-wound models, a sprayable, sustained-release honokiol hydrogel restored SIRT3-related mitochondrial redox signaling and reduced oxidative stress, bacterial burden, and inflammatory matrix degradation. Treatment was associated with improved angiogenesis, granulation, and wound closure; these are preclinical findings, not yet evidence of clinical efficacy.
Chronic Ulcers · Real-World Dressing Evidence
Managing Chronic Wounds With TLC-NOSF Dressings: Evidence From a Prospective Real-Life Patient Cohort
The prospective, multicentre STARTLIFE cohort followed 367 patients with venous leg ulcers or diabetic foot ulcers receiving TLC-NOSF dressings in routine care. Complete healing by 12 weeks was reported in 44.5% of venous ulcers and 36.8% of diabetic foot ulcers; earlier treatment was associated with better outcomes, and the authors report high patient and clinician acceptability.
Diabetic Wounds · Immune-Response Reprogramming
Immune Dysregulation in Chronic Diabetic Wounds: Therapeutic Opportunities for Healing Reprogramming
This review examines how persistent immune imbalance contributes to non-healing diabetic wounds and surveys emerging strategies intended to reprogram the wound environment toward repair. It frames immune modulation as a translational opportunity while underscoring the need to move beyond preclinical promise toward clinically validated wound-healing interventions.
Breast Reconstruction · Human Acellular Dermal Matrix
Analysis of Essence Human Acellular Dermal Matrix Compared With Other Products in Prepectoral Direct-to-Implant Reconstruction
This single-institution prospective review compared three human acellular dermal matrices in 487 immediate prepectoral direct-to-implant cases. Adjusted analyses found no significant differences in infection, noninfectious complications, seroma, skin necrosis, drain duration, or reconstructive failure, despite the Essence cohort including patients with more baseline risk factors.
Skin Repair · Stem-Cell Exosomes
Application of Stem Cell-Derived Exosomes in Skin Wound Healing: Mechanisms, Prospects, and Challenges
This review synthesizes proposed roles for stem-cell-derived exosomes in skin repair, including delivery of bioactive proteins, RNAs, and lipids that may affect inflammation, angiogenesis, and tissue regeneration. It also considers the delivery, manufacturing, and evidence gaps that must be addressed before these cell-free approaches can be translated reliably.
Extracellular Vesicles · Non-Human Sources
Gift of Nature: Non-Human-Derived Exosomes Showing Application in Tissue Regeneration and Engineering
The review surveys non-human-derived exosomes as candidate regenerative carriers, emphasizing reported immunomodulatory, angiogenic, and tissue-repair effects, including periodontal applications. It discusses their potential as alternatives to human-cell-derived products alongside unresolved questions about clinical translation, product consistency, and safety.
Wound Healing · Scar Biology
Extracellular Vesicles in Wound Healing and Scar Formation: Molecular Regulation of Macrophages, Fibroblasts, and Their Crosstalk
This review maps how extracellular vesicles can influence macrophage and fibroblast behavior during normal repair, chronic wounds, and pathological scarring. It highlights that vesicle effects depend on the donor and recipient cell state and local environment, and calls for standardized products, causal validation, and longer-term assessment of wound closure and scar quality.
Facial Rejuvenation · Combined HIFU and RF Microneedling
Combined Fractional Radiofrequency Microneedling and High-Intensity Focused Ultrasound With Focus Dual for Facial Skin Rejuvenation: A 37-Patient Case Series
In this observational series of 37 patients, a six-month protocol combining HIFU and fractional RF microneedling was associated with a 12.1% reduction in median global wrinkle-assessment scores, with larger changes in lax facial regions and no serious adverse events reported. The uncontrolled design and limited follow-up make these results preliminary.
Laser & Light · Evidence Review
Aesthetic Applications of Laser and Light-Based Energy Devices
This narrative review covers laser and light technologies for resurfacing, vascular and pigmentary lesions, scars, and adjunctive treatment. It contrasts ablative CO2 and Er:YAG resurfacing with more tolerable fractional and nonablative options, and emphasizes phototype-specific risk management, careful parameter selection, and individualized combination approaches.
Facial Volumization · Low-Energy Monopolar RF
Adipogenesis and Stem Cell Activation in Facial Fat After Repeated Low-Energy Continuous Monopolar Radiofrequency: Ultrasound, 3D Imaging, and Histological Study
In a prospective single-centre study of 25 lean women, repeated low-energy monopolar RF was associated with increased facial soft-tissue and fat-layer thickness on ultrasound and 3D imaging at 18 weeks. A biopsy from one participant showed markers consistent with progenitor-cell activation and angiogenesis; the small, uncontrolled study warrants confirmation.
Breast Reconstruction · Implant-Free Fat Grafting
Immediate Breast Reconstruction by Exclusive Autologous Fat Grafting After Prophylactic Mastectomy: A Quantitative and Qualitative Study
This quantitative and qualitative study examines immediate breast reconstruction using autologous fat grafting alone after prophylactic mastectomy. The approach offers an implant-free alternative to conventional flap reconstruction; the indexed record provides no abstract, so patient numbers and outcome estimates are not available in the returned metadata.
Breast Reconstruction · Latissimus Dorsi With Lipofilling
Comparative Study of Myocutaneous Latissimus Dorsi Flap Breast Reconstruction With Implant Versus Lipofilling: Complication Rates and Risk Factors
This two-centre retrospective cohort compared implant-augmented and lipofilled latissimus dorsi reconstruction in 116 patients. Major complication rates did not differ significantly, while the lipofilling group had fewer early infections and no late reconstruction loss due to implant issues in this cohort; prospective studies are needed to confirm the comparison.
Breast Fat Grafting · Retention & Patient-Reported Outcomes
Autologous Fat Grafting for Breast Augmentation and Breast Remodeling: A Systematic Review and Meta-Analysis of Complications, Radiologic Outcomes, Graft Retention, and Patient-Reported Satisfaction
This meta-analysis of 40 studies and 5,684 patients estimated 61.3% mean fat-volume retention at 12 months and 93.1% patient satisfaction; the pooled complication rate was 25.9%, mainly minor radiologic or palpable findings. Heterogeneity was substantial for complication and retention outcomes, so the estimates should be interpreted as variable across techniques and studies.
Chest Wall Reconstruction · Digital-to-Surgical Workflow
An Integrated Digital-to-Surgical Framework for Patient-Specific Chest Wall Resection and Reconstruction Using 3D-Printed Titanium Implants: Proof-of-Concept Study
The four-stage workflow combines CT-based 3D modelling, virtual tumour-margin planning, custom implant design, prototype validation, and titanium additive manufacturing. In six consecutive patients, planned resections required no intraoperative modification; implants fit accurately, and no implant failures or implant-related complications were observed during reported follow-up of 5 months to 5 years.
Plastic Surgery Robotics · Bibliometric Landscape
Global Research Trends in Robotic Applications in Plastic Surgery: A Bibliometric Analysis
This bibliometric analysis included 492 plastic-surgery robotics studies and found that 63% focused on microsurgery, with annual publication output rising to 94 papers in 2025. Da Vinci, Symani, and MUSA were the most frequently reported platforms; the authors emphasize that clinical evaluation must keep pace with growing research activity.