Axillary Surgery · Minimally Invasive
Optimizing the Surgical Paradigm for Axillary Osmidrosis: A Retrospective Cohort Study Integrating Tumescent Suction-Curettage and Direct-Vision Trimming
This newly accepted retrospective cohort study compares a tumescent suction-curettage approach with direct-vision trimming for axillary osmidrosis. The technique pairing is designed to balance complete removal of odor-producing tissue against the wound and scar burden associated with more extensive excision.
Breast Reconstruction · ERAS
The 24-hour DIEP challenge: How ERAS redefines recovery in microsurgical breast reconstruction
This study evaluates an enhanced-recovery pathway aimed at compressing recovery after deep inferior epigastric perforator flap reconstruction into a 24-hour framework. Its practical focus is on perioperative standardization and earlier discharge while maintaining the safety requirements of microsurgical monitoring.
Abdominal Wall · Reconstructive Planning
Abdominal Wall Reconstruction: A Literature Review
This review surveys contemporary strategies for abdominal wall reconstruction, spanning primary closure, mesh reinforcement, component separation, and flap-based approaches. The key planning issue is matching the reconstructive method to defect size, tissue quality, contamination, and the need to restore durable abdominal-wall function.
Brow Reconstruction · Tissue Engineering
The evolving landscape of eyebrow reconstruction
This review frames eyebrow reconstruction as a field moving beyond conventional hair transplantation toward cell-based therapies and tissue engineering. It highlights the continuing challenge of recreating a three-dimensional, directionally oriented brow with durable growth and a natural aesthetic result.
Burn Wounds · Procedural Analgesia
Oral ketamine adjunct for wound care in patients with burn injuries
This newly published burn-care study evaluates oral ketamine as an adjunct during wound-care procedures. The approach is clinically relevant because it seeks to improve analgesia and procedural tolerance while limiting the monitoring burden and opioid exposure associated with deeper intravenous sedation.
Chronic Wounds · Photobiomodulation
Photobiomodulation therapy in the management of chronic wounds: From molecular mechanisms to translational clinical evidence
This review connects photobiomodulation’s molecular effects with the clinical evidence for chronic-wound treatment. It positions wavelength, dose, and delivery parameters as central variables for translating a promising light-based modality into reproducible wound-care protocols.
Diabetic Wounds · Mechanisms
Diabetes and Delayed Wound Healing: Molecular Mechanisms and Dermatological Interventions
This review explains how diabetes disrupts multiple stages of wound repair and then surveys dermatological interventions intended to address those deficits. The clinical implication is a coordinated strategy that considers inflammation, infection, perfusion, and tissue remodeling rather than relying on a single topical treatment.
Chronic Wounds · Oxygen Therapy
Clinical Efficacy and Safety of Portable Continuous Topical Oxygen Therapy for Chronic Wound Management: A Randomised Controlled Trial
This randomized controlled trial tests portable continuous topical oxygen as an adjunct for chronic wound management. Its importance is practical: a portable delivery model could extend oxygen-based therapy beyond specialized facilities, provided healing gains and safety remain consistent in routine care.
Tissue Engineering · Skin Substitutes
Advances in stem cell-based tissue-engineered skin substitutes for wound healing
This review examines stem-cell-based skin substitutes intended to improve coverage and regeneration when conventional autograft supply is limited. It emphasizes the translational gap between promising engineered constructs and dependable clinical products, including vascularization, manufacturing, and long-term integration.
3D Bioprinting · Skin Equivalents
3D bioprinting of skin equivalents: Towards functional wound healing
This review surveys 3D bioprinted skin equivalents designed to reproduce the organization and function of native skin. The field is moving from printable geometry toward functional constructs that can vascularize, integrate, and support durable wound closure.
Bioprinted Skin · Clinical Translation
Bioprinted skin: from lab bench to clinic, what matters now and what is next
This perspective places bioprinted skin at the intersection of tissue engineering and reconstructive surgery. It argues that clinical progress will depend not only on printing resolution, but also on bioink performance, vascular integration, regulatory readiness, scalable manufacturing, and meaningful patient outcomes.
ADM · Diabetic Wounds
Human cell-derived dermal-specific interwoven extracellular matrix for diabetic wound healing
This study develops a dermal-specific interwoven extracellular-matrix scaffold derived from human cells for diabetic wound repair. The design aims to provide a more physiologic regenerative substrate than a generic dressing, with matrix architecture and biologic signaling treated as linked therapeutic variables.
Exosomes · Skin Wounds
Application of stem cell-derived exosomes in skin wound healing: mechanisms, prospects, and challenges
This review describes mesenchymal-stem-cell-derived exosomes as nanoscale carriers of proteins, RNAs, and lipids that can reproduce part of the parent cell’s regenerative signaling without delivering whole cells. It emphasizes the remaining translational barriers—manufacturing consistency, dosing, delivery, and clinical validation—before routine wound-care use.
Exosomes · Cell-Free Therapy
The use of therapeutic exosomes for in vivo wound healing
This review evaluates therapeutic exosomes as cell-free agents for wound healing in living models. It focuses on how extracellular-vesicle cargo can influence inflammation, angiogenesis, and matrix remodeling while underscoring the need for standardized preparations and better clinical evidence.
Stem Cells · Mechanically Conditioned Scaffolds
Mechanical stretch loading of BMSCs-PLCL composite scaffolds accelerate diabetic wound healing by protecting endothelial cells and promoting angiogenesis
This preclinical study combines bone-marrow mesenchymal stem cells with a PLCL nanofiber scaffold and applies cyclic mechanical stretch before treatment. The engineered construct is intended to protect endothelial cells and amplify angiogenesis, illustrating how physical conditioning may improve a cell-scaffold therapy for diabetic wounds.
Exosomes · Scarless Healing
Mesenchymal Stem Cells-Derived Exosomes: Next-Generation Nanomedicines Toward Scarless Wound Healing
This review considers mesenchymal-stem-cell-derived exosomes as a next-generation, cell-free strategy for improving wound repair and limiting scar formation. The opportunity lies in targeted delivery of regenerative signals; the challenge is converting mechanistic and preclinical promise into controlled, reproducible clinical products.
RF Microneedling · Device Safety
Analysis of US Food and Drug Administration Data on Adverse Events Associated With Radiofrequency Microneedling
This analysis reviews FDA MAUDE reports associated with radiofrequency microneedling, with attention to treatment locations and reported adverse events. The signal is a reminder that device safety depends on anatomy, energy settings, technique, and informed consent—not only on the label “minimally invasive.”
Laser · Skin Rejuvenation
Repositioning Non-Ablative Fractional Lasers - Molecular and Histological Insights from a scoping review
This scoping review reassesses non-ablative fractional lasers for rejuvenation and scar treatment through molecular and histologic evidence. The authors’ framing supports parameter-specific treatment selection, linking controlled dermal injury to collagen remodeling while keeping downtime and skin phenotype in view.
Lasers · Comparative Effectiveness
Comparative Efficacy and Safety of Laser Versus Chemical Peels for Skin Rejuvenation
This comparative review evaluates laser resurfacing against chemical peels for skin rejuvenation across efficacy and safety outcomes. The evidence supports improvement with both modalities, but choice should be individualized to the target condition, skin type, depth of treatment, and tolerance for recovery.
RF Microneedling · Evidence Synthesis
Effectiveness of Radiofrequency Microneedling in the Treatment of Dermatological Conditions: A Systematic Review
This systematic review synthesizes the clinical literature on radiofrequency microneedling across dermatologic indications. Its value is in separating platform-level enthusiasm from indication-specific evidence and in highlighting the importance of treatment parameters, comparator choice, and standardized endpoints.
Breast Reconstruction · Staged Flaps
The FAST Protocol: A Novel Approach for Staged Autologous Breast Reconstruction
This Plastic and Reconstructive Surgery article introduces a staged protocol for autologous breast reconstruction, addressing the persistent debate over ideal timing and sequencing. The approach may give teams more control over tissue preparation and patient recovery, but its value will depend on reproducibility beyond the originating practice.
Breast Reconstruction · Radiotherapy
Postmastectomy Radiotherapy in Immediate Autologous Breast Reconstruction: A Patient-Reported and Clinical Outcomes Study
This patient-reported and clinical outcomes study examines immediate autologous reconstruction in the setting of postmastectomy radiotherapy. It adds decision-relevant evidence to counseling about satisfaction, complications, and the trade-offs of proceeding with reconstruction before adjuvant treatment is complete.
Breast Reconstruction · Thigh Flaps
Beyond the DIEP Flap: Thigh-Based Autologous Breast Reconstruction
This review examines thigh-based donor sites as alternatives when abdominal tissue is unavailable or unsuitable for autologous breast reconstruction. It supports a broader donor-site algorithm that includes profunda artery perforator and related thigh flaps, while acknowledging the planning and patient-selection constraints of each option.
Fat Grafting · Cell Enrichment
Adipose-Derived Stem Cell-Enhanced versus Conventional Fat Grafting for Breast Reconstruction: A Systematic Review and Meta-Analysis
This systematic review and meta-analysis compares adipose-derived stem-cell-enhanced fat grafting with conventional fat grafting for breast reconstruction. The central question is whether cellular enrichment improves retention and safety enough to justify added processing complexity and unresolved translational concerns.
AI · Clinical Governance
From Innovation to Integration: Responsible Integration of Artificial Intelligence in Plastic Surgery
This perspective shifts the AI conversation from novelty to responsible integration in plastic surgery. It highlights the practical requirements for deployment—validated datasets, bias monitoring, transparent performance limits, clinician oversight, and workflow design that keeps accountability with the care team.
AI · Robotics · Cosmetic Practice
Technological Integration in Aesthetic Practice: A Systematic Review of Artificial Intelligence, Augmented Reality and Robotics in Cosmetic Procedures
This systematic review screened 12,316 studies and included 55 clinical papers on AI, augmented reality, and robotics in cosmetic procedures. Most studies used AI for skin assessment, volumetric planning, or communication; fewer addressed risk prediction, and the overall evidence quality for robotics and augmented reality remained low to moderate.
3D Bioprinting · Wound Care
Clinical trials on 3D bioprinted scaffolds for lower extremity vascular, diabetic and pressure ulcers: A systematic review
This systematic review identified eight human studies of 3D-bioprinted scaffolds for lower-limb ulcers, including two randomized trials and six single-arm studies involving 139 patients. The reported epithelialization gains and absence of treatment-related serious adverse events are encouraging, but small samples, short follow-up, and variable methods still limit confidence.
Intraoperative Bioprinting · Vascularization
Coupling intraoperative bioprinting and surgical micropuncture for synergistic scaffold vascularization
This Biomaterials study couples intraoperative bioprinting with surgical micropuncture to address vascularization of printed scaffolds. The concept moves bioprinting toward the operating field, where defect-specific fabrication and deliberate vessel access could improve integration, though translation remains dependent on reliable bioinks and surgical workflow.