Reconstructive Surgery · ERAS
Do multidisciplinary ERAS protocols improve flap reconstruction outcomes? A structured review of efficacy, implementation challenges, and specialty-driven adaptations
This structured review finds that enhanced-recovery pathways in breast, head and neck, pelvic, and lower-limb flap reconstruction are generally associated with shorter hospital stays, earlier mobilization or feeding, and lower opioid exposure without a clear increase in flap compromise or reoperation. The authors recommend adapting bundles to flap type, comorbidity burden, and reconstructive goals, then auditing local safety and patient-reported outcomes rather than adopting a universal protocol.
Rhinoplasty · Preservation
Preservation Rhinoplasty: A Decade of Progress and Technical Refinement
This Aesthetic Surgery Journal editorial reviews a decade of preservation rhinoplasty, a philosophy that has moved from a relatively new concept toward broad international adoption. The discussion emphasizes how technical refinements can preserve native nasal structures while addressing aesthetic and functional goals, giving surgeons a framework for selecting preservation, structural, or hybrid maneuvers.
Breast Reconstruction · Microsurgery Outcomes
Have Outcomes Improved in Microsurgical Breast Reconstruction? A 7-Year Analysis of the German Society of Plastic, Reconstructive, and Aesthetic Surgeons
This prospective quality-assessment analysis spans 5,671 microsurgical flaps in 4,909 patients across 22 certified German centers from 2011 to 2018. The report finds that overall flap-loss rates remained stable over the study period, providing a large multicenter benchmark for counseling, quality improvement, and evaluating whether technical progress has translated into fewer major failures.
Facial Reconstruction · Local Flaps
Functional and aesthetic outcomes of local flaps vs full-thickness skin grafts in facial defect reconstruction
This recent comparative study examines local flaps versus full-thickness skin grafts for facial defects. Local flaps retain native vascularity and may better match adjacent tissue, while grafts depend on revascularization from the wound bed; the comparison therefore focuses on the trade-offs among healing, color and texture match, function, and aesthetic satisfaction.
Diabetic Wounds · Immunology
Immune Dysregulation in Chronic Diabetic Wounds: Therapeutic Opportunities for Healing Reprogramming
This review frames chronic diabetic wounds as an immune-regulation problem in which persistent inflammation and impaired coordination of repair cells prevent progression through normal healing phases. Its focus on macrophage polarization and therapeutic reprogramming points toward interventions that resolve inflammation while restoring angiogenesis and tissue repair, rather than treating infection or dressings in isolation.
Chronic Wounds · Infection Biology
Infection-driven proliferative phase impairment in chronic wounds: mechanisms and therapeutic opportunities
This review synthesizes evidence that virulence-factor activity, biofilm persistence, and host immune-metabolic dysregulation converge to stall the proliferative phase of chronic wound healing. The proposed therapeutic direction is sequential and multimodal: control infection and biofilm, then restore repair signaling and cell-cycle activity so the wound can leave an arrested state.
Diabetic Wounds · Mechanisms
Diabetes and Delayed Wound Healing: Molecular Mechanisms and Dermatological Interventions
This International Wound Journal review summarizes how diabetes disrupts the molecular and cellular steps required for repair and surveys dermatological interventions intended to address those deficits. The clinical takeaway is that diabetic wound care needs coordinated management of inflammation, infection, vascular impairment, and defective tissue remodeling rather than a single topical solution.
ADM · Deep Burns
Micro-structured porcine acellular dermal matrix: novel wound dressing promoting the repair of deep burn wounds
This study develops a micro-structured porcine acellular dermal matrix to address the limited cell infiltration and angiogenesis of a naturally dense dermal scaffold. The engineered dressing is evaluated as a strategy to improve repair of deep burns, making matrix architecture—not only source material—a clinically relevant design variable.
Skin Substitutes · Complex Defects
DS26 Biodegradable Temporising Matrix: a synthetic tissue substrate as an alternative to local complex surgical reconstruction of excisional skin cancer defects
This report presents a biodegradable temporising matrix as a synthetic tissue substrate for selected excisional skin-cancer defects that might otherwise require complex local reconstruction. The approach is notable for separating temporary dermal replacement from definitive coverage, potentially broadening reconstructive options when local tissue is limited.
ADM · Matrix Processing
Supercritical Carbon Dioxide-Processed Acellular Dermal Matrix Patch for Enhanced Wound Healing
This preclinical study evaluates a supercritical-carbon-dioxide-processed acellular dermal matrix patch designed to preserve a wound-compatible scaffold while improving healing performance. The work highlights processing conditions as a potentially important determinant of matrix structure, biocompatibility, and regenerative activity.
Skin Substitutes · Translational News
Will the latest skin substitutes revolutionize the treatment of burns and other wounds?
This Nature news feature surveys emerging skin substitutes for burns and other wounds, where replacing multiple layers of injured tissue remains difficult and donor skin is limited. It places engineered and laboratory-expanded materials in the broader translational context: promising coverage technologies still need durable integration, scalable production, and convincing clinical outcomes.
Exosomes · Skin Wounds
Application of stem cell-derived exosomes in skin wound healing: mechanisms, prospects, and challenges
This review describes mesenchymal-stem-cell-derived exosomes as nanoscale carriers of proteins, RNAs, and lipids that can reproduce part of the parent cell's regenerative signaling without delivering whole cells. It synthesizes mechanisms relevant to wound repair and emphasizes the remaining translational barriers, including manufacturing consistency, dosing, delivery, and clinical validation.
Exosomes · Facial Regeneration
Exosomes in Cutaneous Wound Healing and Facial Skin Regeneration: Clinical and Translational Perspectives
This clinical and translational review examines exosome cargo as a regulator of inflammation, angiogenesis, and extracellular-matrix remodeling in cutaneous wound healing and facial skin regeneration. The article is useful for separating strong mechanistic rationale from the still-developing clinical evidence base in aesthetic and reconstructive applications.
Stem Cells · Biomaterial Scaffolds
Mechanical stretch loading of BMSCs-PLCL composite scaffolds accelerate diabetic wound healing by protecting endothelial cells and promoting angiogenesis
This preclinical study combines bone-marrow mesenchymal stem cells with poly(L-lactic-co-ε-caprolactone) nanofiber scaffolds and applies cyclic mechanical stretch before treatment. The engineered construct is designed to protect endothelial cells and improve angiogenesis, illustrating how mechanical conditioning may amplify a cell-scaffold therapy for diabetic wounds.
Exosomes · Dermatology
Exosomes in Dermatology
This review places exosomes in a broader dermatology context, covering their effects on keratinocytes, fibroblasts, pigmentation pathways, and immune signaling. Wound healing remains the strongest evidence area, but the authors also outline how extracellular-vesicle biology is being explored for scar modulation and other skin conditions.
Energy-Based Devices · Scar Care
Consensus on energy-based devices for keloids and hypertrophic scars: A Latin American Delphi study
A Delphi panel of 22 Latin American dermatologists reached consensus for 21 of 23 clinical scenarios involving lasers, energy-based devices, and combination therapies for keloids and hypertrophic scars. The consensus favors indication- and scar-stage-specific protocols, with early and inflammatory scars often directed toward vascular-targeting devices rather than indiscriminate energy delivery.
Home Devices · Facial Rejuvenation
Home-Based Dermatologic Devices for Acne and Facial Rejuvenation: A Scoping Review
This scoping review evaluates clinical evidence for home-use devices in acne and facial rejuvenation, a rapidly expanding category whose convenience can outpace its evidence base. The authors emphasize that safety and efficacy vary across device types and indications, making patient selection, realistic expectations, and clear usage guidance central to responsible adoption.
Laser · Parameter Selection
Strategic selection of multi-parametric laser settings and clinical endpoints in dermatology: an engineering-to-clinical review
This review connects laser physics to clinical decision-making by organizing platforms according to spectral domain and indication, including picosecond and Q-switched systems for tattoos and lasers for vascular, pigmentary, and resurfacing concerns. Its central message is that parameter selection and measurable endpoints should be engineered together, rather than treating device choice as a brand-level decision.
Laser · Acne Scars
Acne Laser Devices in Dermatology
This review summarizes the role of laser devices in acne and acne-scar management, with fractional and radiofrequency platforms remaining especially relevant to scar remodeling. It reinforces the need to match energy modality and treatment parameters to active disease, scar phenotype, skin phototype, and the patient's tolerance for downtime.
Breast Reconstruction · Thigh Flaps
Beyond the DIEP Flap: Thigh-Based Autologous Breast Reconstruction
This Plastic and Reconstructive Surgery review examines thigh-based donor sites as alternatives when abdominal tissue is unavailable or unsuitable for autologous breast reconstruction. The discussion supports a broader donor-site algorithm that includes profunda artery perforator and related thigh flaps, while acknowledging technical planning and patient-selection constraints.
Autologous Augmentation · Dermoglandular Flaps
Dermoglandular flaps for autologous augmentation during mastopexy after breast implant explantation: a five-year retrospective study
This five-year retrospective study evaluates dermoglandular flaps as an autologous volume strategy during mastopexy after implant removal. The technique is relevant to explant patients who want reshaping without a new implant, but its outcomes should be interpreted in the context of careful tissue-preservation and individualized flap design.
Adipose Tissue · Reconstruction
Adipose tissue for reconstruction and wound healing: applications, challenges, and future directions
This review surveys adipose tissue as an accessible source for reconstructive and regenerative medicine, spanning fat grafting, stromal-cell biology, and wound-healing applications. It balances the material's clinical versatility against unresolved challenges in graft survival, processing standardization, vascularization, and translating regenerative signals into predictable outcomes.
Fat Grafting · Radiation Effects
Florid inflammatory reaction after fat grafting into an irradiated DIEP-reconstructed breast mimicking cancer recurrence
This case report describes an intense inflammatory reaction with indurated erythematous nodules after fat grafting into a previously irradiated DIEP-reconstructed breast, clinically mimicking recurrence. The lesions resolved conservatively, but the report reinforces imaging and biopsy of suspicious findings because radiation-damaged tissue can produce unusual post-grafting reactions.
AI · Evidence Mapping
Parallels of Progress: Plastic Surgery Literature and Artificial Intelligence
This perspective examines the parallel growth of plastic-surgery scholarship and artificial-intelligence methods, using the relationship between the two literatures as a lens on where the field is heading. Its value is strategic rather than procedural: AI adoption will depend on whether research quality, clinical validation, and governance develop as quickly as publication volume.
AI · Robotics · Cosmetic Practice
Technological Integration in Aesthetic Practice: A Systematic Review of Artificial Intelligence, Augmented Reality and Robotics in Cosmetic Procedures
This systematic review screened 12,316 studies and included 55 clinical papers on AI, augmented reality, and robotics in cosmetic procedures. Most included studies used AI image analysis for skin assessment, volumetric planning, or communication; fewer addressed risk prediction, while robotics and AR supported precision and navigation but rested on overall low-to-moderate methodological quality.
AI · Clinical Translation
State of the Art of Artificial Intelligence in Plastic Surgery
This review assesses large language models, generative AI, and neural networks across plastic-surgery applications such as planning, automation, and postoperative assessment. The clinical opportunity is substantial, but the article keeps the implementation question in view: reliable datasets, external validation, bias control, and workflow integration matter as much as model performance.
Robotics · Reconstructive Surgery
Robot-Assisted Surgical Technology in Plastic Surgery: Evolution, Clinical Applications, and Future Perspectives
This review traces robot-assisted surgery across plastic and reconstructive applications, emphasizing enhanced precision and stability compared with conventional techniques. It presents robotics as an emerging augmentation layer for selected procedures while noting that cost, training, evidence quality, and integration into routine practice remain limiting factors.