Flap Reconstruction · ERAS
Do multidisciplinary ERAS protocols improve flap reconstruction outcomes? A structured review of efficacy, implementation challenges, and specialty-driven adaptations
This structured review found ERAS pathways were generally associated with shorter hospital stays, earlier mobilization or feeding, and less opioid exposure across breast, head-and-neck, pelvic, and limb flap reconstruction. Flap compromise, readmission, and return to theatre were not generally worse, but heterogeneous bundles and mostly observational evidence support local auditing and flap-specific adaptation rather than a universal protocol.
Breast Reconstruction · Donor-Site Closure
TPT 4.16 The Parachute and Pico: A Technique of Barbed Quilting that Enables Ergonomic, Accurate, Aesthetic and Efficient Abdominal Closure for DIEP Breast Reconstruction
The Parachute and Pico modification temporarily suspends the abdominal apron with staples so one surgeon can perform progressive-tension barbed quilting, followed by negative-pressure dressing. In 31 consecutive DIEP patients versus 31 prior controls, mean operative time fell from 6 hours 49 minutes to 6 hours 2 minutes and hospital stay from 3.6 to 3.1 days, with no technique-attributed complications.
Breast Reconstruction · Nipple Reconstruction
Costal cartilage-supported modification of the delta flap for nipple reconstruction after latissimus dorsi flap breast reconstruction
This technical report describes reinforcing a delta-flap nipple reconstruction with costal cartilage after latissimus dorsi breast reconstruction. The approach is intended to improve structural projection and durability; the academic record provides the technique title and publication metadata but no abstract, so comparative efficacy cannot yet be assessed.
Head & Neck · Flap Reconstruction
Head and Neck Cancer Reconstruction with Flap: A Comparative Study of Restoration of Internal Lining VS No Restoration
In a 48-patient comparative study, restoring the internal lining during head-and-neck flap reconstruction was associated with fewer complications: fistula occurred in 8.3% versus 29.2% without restoration, and flap necrosis in 4.2% versus 12.5%. The restoration group also showed better swallowing, speech, oral-feeding, and overall functional outcomes, although the nonrandomized design limits causal inference.
Venous Leg Ulcers · Amniotic Membrane
Hypothermically stored amniotic membrane compared to standard of care for complex venous leg ulcers: a randomised controlled clinical trial
This prospective multicenter randomized trial enrolled 206 patients with challenging venous leg ulcers after a four-week run-in. Adding hypothermically stored amniotic membrane to standard care significantly improved closure at weeks 12 and 16 and increased reductions in wound area, depth, and volume versus standard care alone.
Chronic Wounds · Photobiomodulation
Clinical dosimetry and efficacy of LED photobiomodulation for chronic lower-limb wound healing: a systematic review of randomized trials
A systematic review of six randomized trials found LED photobiomodulation may reduce wound area, improve wound-bed quality, and increase microcirculation, particularly in diabetic foot ulcers. Evidence certainty was very low because wavelengths and energy densities varied widely, including a high-dose study with no benefit; standardized dose–response trials are needed.
Chronic Wounds · Virtual Care
Virtual care for chronic wounds in residential aged care settings: A scoping review
Mapping 17 studies, this scoping review found telehealth and store-and-forward models were commonly used for diagnosis and management and were generally viewed as safe and acceptable by residents, families, and staff. Reliable internet, stable staffing, training, and adjunct in-person care were key implementation conditions, highlighting an operational pathway for extending specialist wound input.
Diabetic Foot Ulcers · Combination Therapy
Combination therapy strategies for diabetic foot ulcers: synthesizing antibiotics, growth factors, and nanocarriers in modern wound management.
This review examines combining antibiotics, growth factors, and nanocarriers to address biofilms, impaired angiogenesis, oxidative stress, and persistent inflammation in diabetic foot ulcers. Stimuli-responsive and sequential-release systems may synchronize antimicrobial and regenerative actions, but biosafety, scale-up, regulation, and long-term clinical evidence remain major barriers.
Breast Surgery · Acellular Dermal Matrix
Long-term Outcomes of Acellular Dermal Matrix Use in Breast-Conserving Surgery: A Single-Institution Study.
This newly indexed single-institution study evaluates long-term outcomes after acellular dermal matrix use in breast-conserving surgery. The academic record supplies the title, authors, date, and DOI but no abstract, so the brief flags the study as an outcomes report without inferring comparative results.
Dermal Substitute · Full-Thickness Defects
Wound Healing Efficacy of Novel Dermal Substitute TissueDerm Graft® in Full-Thickness Skin Defects
In a minipig full-thickness defect model, the collagen-based TissueDerm Graft® was compared with bovine acellular dermal matrix alongside split-thickness skin grafting. TissueDerm showed uniform collagen architecture and elastin, favorable healing without excessive inflammation or scarring, and better visual outcomes than skin grafting alone or grafting with Matriderm®.
Dermal Scaffolds · Integra / NovoSorb
Modern materials for dermal skin substitute: principles of production and modern acellular products based on them
This review describes design principles for artificial acellular dermal scaffolds and surveys clinically used products including Integra, Giamatrix, SmartMatrix, and NovoSorb. It emphasizes restoration of dermal structure as a determinant of durable healing and argues that translating international scaffold experience could improve access to locally produced substitutes.
Pediatric Reconstruction · Tissue Engineering
Advancements in pediatric tissue engineering: scaffold-based and cell-driven approaches
This recent review surveys scaffold-based and cell-driven approaches in pediatric tissue engineering, with relevance to the distinctive growth, remodeling, and developmental needs of children. The academic record provides no abstract, so the item is included as a high-recency field overview rather than a claim of clinical efficacy.
Stem Cells · Graft Survival
From neural loss to regeneration: modulating cell death to enhance pluripotent stem cell graft survival and integration.
This translational review focuses on why pluripotent stem-cell grafts fail to survive or integrate reliably in neural repair. It proposes combining modulation of programmed cell death and RAS signaling with mitochondrial optimization and biocompatible scaffolds to improve graft maturation and network integration.
Craniofacial Bone · 3D Scaffold
3D printed nano-hydroxyapatite scaffold combined with BMSCs cell sheet containing concentrated growth factor (CGF) for enhancing bone regeneration.
In a rat cranial-defect model, a 3D-printed porous nano-hydroxyapatite scaffold wrapped with concentrated-growth-factor BMSC cell sheets outperformed either component alone on bone formation, mineral density, vascularization, and osseointegration. The composite combines mechanical support with osteogenic signaling, but remains preclinical.
Ear Reconstruction · Stem Cells / Exosomes
Ear Cartilage Reconstruction: From Regenerative Medicine to Reconstructive Surgery.
This review links conventional rib-cartilage reconstruction with stem-cell differentiation, natural and synthetic scaffolds, and exosome engineering for ear cartilage regeneration. It highlights the promise of 3D scaffold systems while stressing the need for standardized protocols, controlled comparisons, manufacturing quality, and regulatory review before clinical translation.
Radiofrequency · Skin Laxity
Radiofrequency technology as an anti-aging intervention: clinical efficacy in reversing senescence-driven skin laxity and age-related dermal degeneration
In a retrospective comparison of 84 aging patients, both monopolar and multipolar radiofrequency improved skin-elasticity measures, but multipolar treatment produced larger three-month gains in R2, R5, and R7 and higher aesthetic-assessment scores. The findings support multipolar RF as a potentially stronger option, while the retrospective design and limited follow-up call for controlled validation.
RF-Assisted Liposuction · Technique
Liposuction and Skin Tightening by Plastic Internal Low-angular Retraction Technique to Direct Skin Retraction with Monopolar Radiofrequency
This prospective observational cohort describes the PILAR technique, which directs subdermal tissue retraction during monopolar RF-assisted liposuction. Among 100 patients, PILAR used substantially less energy than conventional RF-assisted liposuction while maintaining comparable contouring and high patient satisfaction; controlled studies are still needed.
Periorbital Rejuvenation · RF Microneedling
Radiofrequency microneedling for skin rejuvenation of the periorbital region – a prospective, clinical study
In a prospective evaluator-blinded study of 25 patients treated with one to three radiofrequency microneedling sessions, mean wrinkle reduction was 25.3% infraorbitally and 37.3% at crow’s feet at six-month follow-up. Transient erythema and edema were universal but resolved within days; no severe adverse events occurred, and larger comparative studies are needed.
Light-Based Devices · IPL
Clinical Application of Intense Pulsed Light: An Update and Critical Review
This 2024–2026 evidence review finds the strongest contemporary support for IPL in erythematotelangiectatic rosacea and meibomian-gland dysfunction, with emerging applications in rejuvenation, melasma, scar modulation, and hair reduction. It also emphasizes unresolved questions around patient selection, parameter customization, durability, and long-term safety.
Fat Grafting · Graft Biology
Porous Architecture and Pressure-Induced Latent Injury: New Insights into Large-Volume Fat Grafting.
A three-dimensional human adipose model and nude-mouse transplantation study found large-volume graft survival depended on an approximately 8-mm viable porous layer. Pressure reduced solute permeability and viability and increased later fibrosis from 22.1% in controls to 53.3% at the highest tested pressure, suggesting that gentle handling and implantation may be biologically important.
Fat Grafting · Biomaterial Adjunct
Recombinant Humanized Type III Collagen Enhances Fat Graft Retention by Promoting Angiogenesis and Adipocyte Viability in a Nude Mouse Model.
In a nude-mouse model, adding recombinant humanized type III collagen to lipoaspirate reduced volume loss, with the strongest retention and structural integrity near 4 mg/mL. The adjunct increased vascularization, adipocyte viability, and pro-angiogenic signaling, making it a promising but still preclinical strategy for standardizing fat-graft retention.
Breast Reconstruction · Perforator Flaps
Superior Gluteal and Lumbar Artery Perforator Flaps in Autologous Breast Reconstruction: A Systematic Review and Meta-Analysis.
A PRISMA review of 23 studies covering 475 SGAP and 440 LAP patients found lower pooled flap loss and overall complications with SGAP than LAP, while LAP nearly always required vessel grafting. Both are viable nonabdominal options, but the differing technical demands and donor-site risks argue for individualized flap selection.
Pediatric Craniofacial · Dermal Fat Grafting
Restoring balance in a growing face: Two-stage dermal fat grafting for pediatric hemifacial microsomia
This case report describes two-stage, compartment-based dermal fat grafting in a six-year-old with hemifacial microsomia, using groin donor sites and thread-pull stabilization. At six months after the second procedure, estimated graft retention was 75–80% with stable symmetry and no complications, though the single case cannot establish generalizability.
AI · Plastic Surgery Evidence
Artificial Intelligence in Plastic Surgery: A Bibliometric and Visual Analysis of the 100 Most-Cited English-Language Publications
A bibliometric analysis of the 100 most-cited AI publications in plastic surgery found 2,701 total citations and a sharp post-2022 publication surge. Patient education and large-language-model consultation were the largest thematic cluster, while ethics/governance and outcome prediction were also prominent; aesthetic surgery led specialty representation, with craniofacial and breast reconstruction each contributing 21%.
Robotics · Microsurgery
Global research trends and thematic evolution in robotic microsurgery and supermicrosurgery: a bibliometric and visualisation study
This bibliometric and visualization study maps the global literature and thematic evolution of robotic microsurgery and supermicrosurgery. The record provides the study title, authors, date, and DOI but no abstract; its relevance is strategic, identifying where robotic precision and supermicrosurgical applications are concentrating without implying clinical-effect claims.
3D Bioprinting · AI-Native Systems
The Next Phase of 3D Bioprinting: AI-Native Systems—A Narrative Review
Reviewing 365 publications, this paper argues bioprinting is moving from AI-augmented tools toward AI-native systems with continuous learning, multimodal sensing, and biologically closed control loops. Clinical-translation papers far outnumbered cell-viability prediction studies, underscoring the need for open datasets, shared biological metrics, cross-lab validation, and early regulatory engagement.
3D Bioprinting · Skin Regeneration
Recent advances and challenges in 3D bioprinting for skin tissue regeneration
This review evaluates bioinks and printing platforms for skin repair, highlighting opportunities in chronic wounds, cosmetically critical areas, extensive burns, and pharmaceutical testing. It identifies persistent gaps in vascularization, nerve and appendage regeneration, elastin, immune-material interactions, GMP manufacturing, scalability, and cost, with AI-driven optimization as one route forward.